Endoscope and method for vein removal

ABSTRACT

An endoscope for use in harvesting blood vessels includes a scope body of the type having a lumen extending longitudinally therethrough which itself has a proximal and a distal end. The endoscope includes means for viewing an area adjacent the distal end of the lumen, and the lumen has a lateral dimension of a size sufficient to accommodate the blood vessel being harvested and at least one tool for use in harvesting the blood vessel. A first end of the blood vessel section to be harvested is exposed through an incision in the patient&#39;s body. A dissecting tool and a gripping tool are inserted through the lumen of the endoscope and used to dissect the blood vessel away from the surrounding connective tissue of the patient&#39;s body, using the viewing means of the endoscope to view this dissection in process within the patient&#39;s body. Additional tools are provided for use through the lumen of the endoscope to remove body fluids and coagulate bleeding tissue, and to sever side branches from the blood vessel to be harvested, as well as to sever a distal end of the blood vessel to be harvested when a desired length of blood vessel has been dissected. Only a single small incision in the patient&#39;s body is necessary to harvest a relatively long length of blood vessel in a precise and controlled manner through endoscopic vision using the inventive endoscope and its related tools. 
     .Iadd.The questions raised in reexamination request No. 90/004,301, filed Jul. 12, 1996, have been considered and the results thereof are reflected in this reissue patent which constitutes the reexamination certificate required by 35 U.S.C. 307 as provided in 37 CFR 1.570(e). .Iaddend.

BACKGROUND OF THE INVENTION

The present invention relates generally to surgical instruments. Inparticular, the present invention relates to a method and instrument forharvesting a section of a blood vessel from a patient.

In certain surgical procedures, it is necessary to remove a section of ablood vessel from a patient for use in another part of the patient'sbody or for transplanting into a second patient's body. For example, asection of the saphenous vein may be removed for use in coronary bypasssurgery. Previously, it has been necessary to make an incision along thefull length of the vein section to be removed. The vein is then freed bysevering and ligating the branches of the vein, after which the sectionof the vein can be removed from the patient. The full length incisionmust then be closed, for example by suturing or staples. Obviously, theharvesting of the vein in this manner leaves disfiguring scars which arecosmetically undesirable. Additionally, the large incision creates arisk of infection to the patient and may not heal properly, especiallywith those patients who have poor circulation in their extremities. Suchan incision may create a chronic wound which will not heal.

Devices for harvesting a section of a blood vessel without creating afull length incision have been suggested. U.S. Pat. No. 4,793,346 toMindich discloses a device for harvesting a section of a blood vessel bymaking only small incisions at opposite ends of the blood vesselsection. The device includes a guide rod which fits inside of the veinsection and a tube having an inner diameter slightly larger than theouter diameter of the vein section to be harvested. The tube has one ormore knife blades at the leading edge which are connected to anelectrical supply. The vein section is removed by making the incisionsufficiently deep so as to expose the ends of the blood vessel sectionto be harvested. The blood vessel is cut to expose one end, the guiderod is inserted inside the blood vessel section, and the tube is placedover the end of the blood vessel section to be removed. The tube is thenpushed along the blood vessel (into the patient) while rotating the tubeto sever the branches of the blood vessel with the knife blades mountedat the leading edge of the tube. Electrical current is supplied to theknife blades to heat the blades and thereby cauterize the ends of thesevered branches of the blood vessel. The procedure is continued untilthe tube has reached the second of the two incisions. The blood vesselis exposed and cut from the patient at the second incision, and the tubeis then removed from the patient with the blood vessel section inside ofthe tube. The blood vessel section is then removed from the tube forfurther treatment and used as desired.

UK Patent Application GB 20 82 459A discloses a device for harvesting asection of a blood vessel similar to that disclosed in the Mindichpatent. Again, two incisions are made, one at each end of the bloodvessel section to be harvested. A guide rod is inserted into the bloodvessel section through one of the incisions and a tube having a cuttingelement at its operative end is passed over the blood vessel section andguide rod assembly. The tube is rotated as it passes over the bloodvessel section to sever the connecting branches. After the tube haspassed the entire length of the blood vessel section, the section is cutaway through the second incision and the tube is removed from thepatient with the harvested section inside the tube.

The blood vessel harvesting devices of the prior art have certaindistinct disadvantages. While the prior art devices eliminate the needfor a full length incision to remove the blood vessel segment, twoincisions, one at each end of the segment to be harvested, are requiredin order to remove the blood vessel segment. For patients likely todevelop chronic wounds, each additional incision increases the risk tothe patient, and it is desirable to keep such incisions as close to thepatient's trunk as possible and to minimize the number and size of suchincisions. Additionally, the prior art devices do not allow for theviewing of the dissection of the blood vessel segment. The physicianoperating the removal device is unable to see the progression of thedissection and must rely on the guide rod inserted within the bloodvessel to guide the cutting instrument in the proper direction. Theinability to view the dissection directly increases the risk of damagingthe blood vessel segment and the risk of causing injury to the patient.

In addition, it is critical that the segment of blood vessel beingharvested is handled with great care since it is destined for reuse(e.g., as an arterial bypass). The blind insertion of a guide rod intothe blood vessel damages and likely destroys the endothelium of thevessel. The prior art devices also have the disadvantage of being unableto adequately close off severed branches of the blood vessel and thusare unable to adequately control bleeding. As a result, the patientsuffers greater blood loss than is necessary. The prior art devices alsomay remove more tissue than is necessary because the size of the cuttingdevice is not readily adaptable to changes in the size of the bloodvessel.

There is a need for an efficient and effective means for harvesting asection of a blood vessel from the body of a patient. Specifically,there is a need for a device that does not require insertion of anycomponent within the vessel being harvested, and that allows directviewing of the dissection of the blood vessel segment while at the sametime minimizing the size of the incision into the patient's body. Such adevice would allow the physician to be much more precise in thisprocedure, minimize the risk of the patient developing a chronic woundthat will not heal, minimize the amount of scarring to the patient'sbody and maintain the internal integrity of the blood vessel beingharvested.

SUMMARY OF THE INVENTION

The present invention is a device and method for harvesting a section ofa blood vessel from a patient's body. The invention includes anendoscope of the type having a scope body with a lumen extendinglongitudinally therethrough, with the lumen having a proximal end and adistal end. The endoscope includes means for viewing an area adjacent tothe distal end of the lumen. The lumen has a lateral dimension of sizesufficient to accommodate a blood vessel and at least one tool for usein harvesting the blood vessel.

This endoscope for harvesting a blood vessel is relativelyuncomplicated. The endoscope allows a section of a blood vessel to beremoved by making only a small incision at one end of the blood vesselsection to be harvested. The incision exposes a first end of the bloodvessel section to be harvested and the first end is inserted through thelumen of the endoscope. The blood vessel is then dissected away fromsurrounding connective tissue of the patient's body with a dissectingtool inserted through the lumen of the endoscope, using the viewingmeans to view the dissection in process as the endoscope is advancedalong the blood vessel into the patient's body.

In one preferred embodiment, the endoscope is used with a tool forligating and cutting branches of the blood vessel segment or a secondend of the blood vessel segment. The tool has a distal operative tipwith means on the distal tip for applying a ligation clip to a sectionof the blood vessel specimen which is to be sealed. There are also meanson the distal tip for cutting the blood vessel segment between the clipand the first end of the blood vessel segment. The tool eliminates therequirement of making a second incision at the second end of the bloodvessel segment to cut the blood vessel segment at the second end so thatit may be removed.

The endoscope is ideally suited for patients likely to develop chronicwounds, such as diabetics or other persons with poor circulation,because only one small incision is required to remove the blood vesselsegment. The endoscope also allows the physician to directly view thedissection of the blood vessel segment. The ability to directly view thedissection allows the physician to conduct the vessel harvestingprocedure much more efficiently and precisely, minimizing the risk ofdamage the blood vessel and minimizing the risk of injury to thepatient.

BRIEF DESCRIPTION OF THE DRAWINGS

The invention will further be described with reference to theaccompanying drawings where like numbers refer to like parts in severalviews, and wherein:

FIG. 1 is a perspective view of the inventive endoscope and some relatedtools, along with a portion of a patient's leg;

FIG. 2 is a side elevational view of a dissecting tool of the presentinvention, with its distal end enlarged in perspective;

FIG. 3 is a side elevational view of a gripping tool of the presentinvention, with its distal end enlarged in perspective;

FIG. 4 is a side elevational view of a ligation-cutting tool of thepresent invention, with its distal end shown enlarged in perspective;

FIG. 4A is a top plan view of the distal end of the ligation-cuttingtool of FIG. 4;

FIG. 4B is a side elevational view of the distal end of theligation-cutting tool of FIG. 4;

FIG. 5 is a side elevational view of a side-biting ligation-cutting toolof the present invention, with its distal end enlarged in perspective;

FIG. 6 is a side elevational view of a suction-coagulator tool of thepresent invention;

FIG. 7 is an enlarged perspective view of the endoscope of the presentinvention;

FIG. 8 is a perspective view of the endoscope of the present invention,showing its two-part assembly;

FIGS. 9-13 are enlarged perspective illustrations showing the distal endof the inventive endoscope and the tools of FIGS. 2-6 in use during theharvesting of a blood vessel; and

FIG. 14 illustrates the partial removal of a partially dissected bloodvessel through a second incision, when a long continuous segment ofblood vessel is desired to be dissected from the patient's body.

While the above-identified drawing figures set forth one preferredembodiment of the invention, other embodiments are also contemplated, asnoted in the discussion. In all cases, this disclosure presents thepresent invention by way of representation and not limitation. It shouldbe understood that numerous other modifications and embodiments can bedevised by those skilled in the art which fall within the scope andspirit of the principles of this invention. It should be specificallynoted that the figures have not been drawn to scale as it has beennecessary to enlarge certain portions for clarity.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

The present invention is a device and method for harvesting a section ofa vessel from a patient's body for use in another part of the patient'sbody or for transplanting into a second patient's body. For example, asection of the saphenous vein may be removed for use in coronary bypasssurgery. The blood vessel needs to be removed without undue damage tothe blood vessel, as well as with minimal damage and trauma to thepatient. Although the description herein is directed to the harvestingof the saphenous vein, it is contemplated that the present invention beused in connection with the efficient and effective harvesting of theother lumens and vessels from a patient's body.

THE TOOLS

In FIG. 1, a saphenous vein 20 (shown in phantom) and endoscope 30 areshown. The saphenous vein 20 travels along the medial side of the foot,leg, and thigh, where it joins with the femoral vein near the groin.

When used to harvest a blood vessel, the endoscope 30 is used inconjunction with several tools. A dissecting tool 100 (FIG. 2) is usedto separate the blood vessel from the surrounding connective tissue. Agripping forceps 150 (FIG. 3) is used by the physician to hold the bloodvessel 20 during the procedure. A ligation-cutting tool 200 (FIG. 4) isused when severing side branches 22 from the blood vessel 20. Aside-biting ligation-cutting tool 250 (FIG. 5) is used to transect theblood vessel 20 when the dissection is completed. Finally, asuction-coagulator tool 300 (FIG. 6) is used to control bleeding duringthe procedure. Each of these tools is described in detail in thesucceeding discussions.

As illustrated in FIGS. 1 and 7, the endoscope 30 includes an elongatedscope body 34 and a handle 36. A lumen 38 extends longitudinally throughthe scope body 34 and has a cross-sectional shape which is substantiallyelliptical. The lumen 38 is of a size large enough to accommodate theblood vessel 20 which is to be harvested and one or more of the tools100, 150, 200, 250 and 300 longitudinally therein. In one embodiment,the size of the lumen 38 in the scope body 34 is 2 cm wide by 1 cm deepin an elliptical shape, while the scope body 34 itself is 30 to 90centimeters long. Each of the tools is at least 2 cm longer than thescope body 34. As illustrated in FIG. 8, the scope body 34 of theendoscope 30 is selectively securable to the handle 36. The scope body34 can thus be made as a disposable unit to eliminate problems withre-sterilization of the portion of the endoscope 30 that enters thepatient's body. After use, the endoscope is disassembled, the scope body34 disposed of, and the handle 36 (containing power connections,lighting means, etc.) saved for repeated use with a new scope body.Alternatively, the scope body has a longitudinal channel therein forreception of the viewing and illumination portions of the endoscope, sothat those components are reused while the scope body is disposed aftereach use. The scope body is provided in a variety of lengths and sizes(cross-sectional) to accommodate patients of different sizes anddifferent blood vessel lengths.

As seen in FIG. 7, fiber optics illumination source 40 and a fiberoptics viewing device 42 are located at the distal end of the endoscope30 and positioned adjacent each other such that the area immediatelyadjacent the distal end of endoscope 30 can be illuminated and viewed bythe physician. When connected to the handle 36, the source 40 isoperably connected to an external light source 43 by a suitable lighttransmission conduit 44 which extends through the endoscope 30.Similarly, the viewing device 42 is operably connected to an externalmonitor 45 by a suitable image transmission conduit 46 which extendsthrough the endoscope 30. The physician views the area adjacent thedistal end of endoscope 30 using the illumination source 40 and theviewing device 42 by use of the viewing monitor 45 (FIG. 1) which isconnected to the endoscope handle 36 through the conduit 46. The monitor45 may take several forms, such as a television monitor or an eye-pieceworn by the physician, as is conventional. The endoscope body 34 alsohas an irrigation channel 48 extending therethrough. The irrigationchannel is operably coupled to an external source of irrigant 49 via asuitable conduit 50. A distal open end of the irrigation channel ispositioned adjacent the distal ends of the fiber-optic illuminationsource 40 and the viewing device 42, as seen in FIG. 1.

Each of the tools 100, 150, 200, 250 and 300 to be used with theendoscope 30 are of a size small enough to fit through the lumen 38 ofthe scope body 34 while a blood vessel 20 is also in the lumen 38. Thetools 100, 150, 200, 250 and 300 are also long enough to allow thephysician to comfortably manipulate them through the lumen 38 (i.e., thetools 100, 150, 200, 250 and 300 are longer than the lumen 38).

The dissecting tool 100 (FIG. 2) is used to aid in separating the vesselbeing harvested from the surrounding tissue. The dissection tool 100 hasan elongated shaft 105, with a handle 106 attached to the proximal endof the shaft 105 and an annular dissecting ring 110 attached to thedistal end of shaft 105. The dissecting ring 110 is oriented such that aplane defined by the dissecting ring 110 is generally perpendicular tothe longitudinal axis of the shaft 105. The size of dissecting ring 110is large enough to fit over the exterior of the blood vessel 20. Thedissecting ring 110 has a rounded distal edge 112 used to separate theblood vessel 20 from the surrounding connective tissue as the dissectingtool 100 is advanced over the blood vessel 20. The dissecting tool 100is provided in a plurality of sizes for different sizes of bloodvessels. Typical sizes for such tools would have inside diameters of 4mm, 5 mm, and 6 mm.

The gripping tool 150 (FIG. 3) is used to hold and retain the vesselbeing harvested during the procedure. The gripping tool 150 has anelongated shaft 155, with a handle 156 attached to a proximal end of theshaft 155 and a gripping mechanism 160 attached to a distal end of theshaft 155. The handle 156 is preferably a scissors-type handle toactuate the gripping mechanism 160 at the distal end of the body 158 andincludes a latching mechanism 157 which allows the gripping mechanism tobe locked in a set position (e.g., in a "gripping" position). The shaft155 transmits the actuating movement from the handle 156 to the grippingmechanism 160. The gripping mechanism 160 includes a first jaw 162 and asecond jaw 164 which oppose each other. When the gripping handle 156 isoperated by the physician, the first jaw 162 and the second jaw 164 aremoved toward each other and may be used to grip the blood vessel 20between gripping surfaces 166 and 168 thereon. The jaws 162 and 164 aresmall enough to fit through the dissecting ring 110 on the dissectingtool 100.

The ligation-cutting tool 200 (FIGS. 4, 4A and 4B) is used to sever andseal side branches on the vessel being harvested. The ligation-cuttingtool 200 has an elongated shaft 201, with a ligation clip applicator 202and a cutting mechanism 204 at the distal end of the shaft 201. Theligation clip applicator 202 includes a first yoke 208 and a secondopposed yoke 210. Each yoke 208 and 210 is in turn divided into twosections; each yoke 208 and 210 is forked at its distal end, forming twoopposed prongs 212A and 212B on the yokes 208 and 210, respectively. Theprongs 212A and 212B on yokes 208 and 210 are parallel to each other andgenerally aligned with the longitudinal axis of the ligation-cuttingtool 200. The yoke 208 and 210 and the prongs 212A and 212B thereonoppose each other and serve to apply ligation clips 216 (see FIGS. 4Aand 4B) to a side branch 22 being severed. The opposing prongs 212A and212B of each yoke 208 and 210 contain grooves 214A and 214B,respectively, to securely hold a ligation clip 216 therein. When theligation clips 216 are thus held between the opposing prongs 212A and212B of yokes 208 and 210, the generally U-shaped ligation clips 216 aidthe physician in properly aligning the ligation-cutting tool 200 and theside branch 22 to be ligated by providing an abutment for the sidebranch 22 when the side branch 22 is positioned between the yokes 208and 210. When the yokes 208 and 210 are biased towards each other in aconventional manner, the ligation clips 216 are deformed to clamp ontothe side branch 22 therebetween and the blood flow through the sidebranch 22 is halted at two slightly spaced apart points (e.g., two clipsare applied approximately 0.25 inches apart). When the ligation clipapplicator 202 is activated and the yokes 208 and 210 clamp the ligationclips 216 onto the side branch 22, the side branch 22 is also heldsecurely for cutting the side branch 22.

The cutting mechanism 204 on the ligation-cutting tool 200 includes acutting blade 230 aligned between the prongs 212A and 212B and proximalto the ligation clips 216. The cutting blade 230 is normally retracted(as seen in FIGS. 4, 4A and 4B) to allow the side branch 22 to bepositioned properly between the yokes 208 and 210. A cutting edge 232 ofthe blade 230 faces the distal end of the ligation-cutting tool 200, andthe cutting motion of the blade 230 is in a distal direction (e.g.,towards the side branch 22). The blade 230 is wide enough to completelysever the side branch 22 between the two yokes 208 and 210. The cuttingmechanism 204 is activated by the physician (as described below) afterthe side branch 22 has been ligated (i.e., the side branch 22 has beenclipped shut and blood flow halted) and while the side branch is stillheld securely in the yokes 208 and 210. After the blade 230 has severedthe side branch 22, the blade 230 returns into its original retractedposition.

The ligation clip applicator 202 and the cutting mechanism 204 are bothactuated by mechanisms at the proximal end of the shaft 201 of theligation-cutting tool 200. The ligation clip applicator 202 ispreferably actuated by a scissors-type handle 220. By squeezing thescissors-type handle 220, the physician causes each set of prongs 212Aand 212B on the yokes 208 and 210 to be moved together, therebycompressing their respective ligation clips 216 about the side branch 22of the blood vessel 20, as described above. The scissors-type handle 220includes a latching mechanism 222 which serves to secure the handle 220and thus the ligation clip applicator 202 in a closed or clampedposition. While the ligation clip applicator 202 is held in a clampedposition, the cutting mechanism 204 is actuated, preferably by a plunger224 located at the proximal end of the ligation-cutting tool 200. Theplunger 224 is operably connected to the cutting blade 230, and biasedproximally to urge the blade 230 into its normally retracted position.By moving the plunger 224 distally, the physician causes the cuttingblade 230 to likewise move distally and cut the side branch 22 of theblood vessel 20 which is retained between the yokes 208 and 210. Whenthe physician releases the plunger 224, the plunger 224 (and thus thecutting blade 230) retracts to its original position. Manipulation ofthe handle 220 then separates the prongs 212A and 212B, leaving the clipin place on the severed portions of the side branch 22, and theligation-cutting tool 200 is removed or relocated for reuse (the clipsmay be fed into place in the grooves of the prongs from a suitable clipmagazine (not shown) to enable multiple ligations without removing thetool from the body).

The shaft 201 of the ligation-cutting tool 200 is a slender member thatis longer than the lumen 38 of the endoscope 30. A housing 209 coversthose mechanisms on the shaft 201 that transmit the manipulations of thehandle 220 and the plunger 224 at the proximal end of theligation-cutting tool 200 to the clipping and cutting motions,respectively, at the distal end of the ligation-cutting tool 200.

The side biting ligation-cutting tool 250 (FIG. 5) is used to sever andseal the distal end of the vessel being harvested. The side-bitingligation-cutting tool 250 is identical in operation to the ligation tool200, except that the operative components at the distal end of the tool250 are oriented generally normally to the axis of the tool 250. As seenin FIG. 5, the side biting ligation-cutting tool 250 has an elongatedshaft 251, with a ligation clip applicator 252 and a cutting mechanism254 at the distal end of shaft 251. The ligation clip applicator 252includes a first yoke 258 and a second, opposed yoke 260. Each yoke inturn is forked at its distal end, forming two opposed prongs 262A and262B, respectively. The prongs are aligned generally parallel and eachhas inner grooves 264 to retain ligation clips between each opposed pairof prongs 262A and 262B. The structure and operation of the ligationclip applicator 252 is similar to that illustrated in FIGS. 4A and 4Bfor the ligation-cutting tool 200.

The yokes 258 and 260 and the prongs 262A and 262B thereon oppose eachother and serve to apply ligation clips (not shown in FIG. 5) to thedistal end of the segment of the blood vessel being severed. When theligation clips are thus held between the opposing prongs 262A and 262Bof yokes 258 and 260, the generally U-shaped ligation clips aid inpositioning and properly aligning the side biting ligation-cutting tool250 and the blood vessel to be transected by providing an abutment forthe blood vessel when the blood vessel is positioned between the yokes258 and 260. When the yokes 258 and 260 are moved towards each other,the ligation clips are clamped onto the blood vessel therebetween andthe blood flow through the blood vessel is halted at two slightlyspaced-apart points (e.g., two clips are applied approximately 0.25inches apart). When the ligation clip applicator 252 is activated andthe yokes 258 and 260 clamp the ligation clips onto the blood vessel,the blood vessel is also held securely for cutting the blood vessel.

The cutting mechanism 254 on the side biting ligation cutting tool 250includes a cutting blade 280 aligned between the prongs 262A and 262B.Again, the structure of the cutting mechanism for the tool 250 is quitesimilar to that illustrated in FIGS. 4A and 4B for the ligation-cuttingtool 200. The blade 280 is positioned such that a cutting edge 282 ofthe blade 280 does not interfere with the alignment of the blood vesselbetween the yokes 258 and 260. The cutting blade 280 is normallyretracted (as seen in FIG. 5) to allow the blood vessel to be positionedproperly between the yokes 258 and 260. The cutting edge 282 of theblade 280 faces in a transverse direction from the shaft 251 of the sidebiting ligation-cutting tool 250, and the cutting motion of the blade280 is in a transverse direction (e.g., toward the blood vessel). Theblade 280 is wide enough to complete sever the blood vessel between thetwo yokes 258 and 260. The cutting mechanism 254 is activated after theblood vessel has been ligated (i.e., the blood vessel has been clippedshut and blood flow halted) and while the blood vessel is still heldsecurely in the yokes 258 and 260. After the blade 280 has severed theblood vessel, the blade 280 returns to its original retracted position.

The primary difference between the tool 200 and tool 250 is that thedistal operative portion of the tool 250 is oriented at an anglegenerally ninety degrees opposed to the axis of the shaft 251 of thetool 250. The yokes 258 and 260 are thus oriented to straddle a bloodvessel extending generally parallel to the shaft 251 to apply ligationclips thereto. After clips are applied, the yokes continue to hold theblood vessel to permit severing of the vessel using the blade 280. Otherthan the revision in orientation of the distal portion of theligation-cutting tool 250, it operates in the same manner as theligation-cutting tool 200.

The ligation clip applicator 252 and the cutting mechanism 254 are bothactuated by mechanisms at the proximal end of the shaft 251 of theligation-cutting tool 250. The ligation clip applicator 252 ispreferably actuated by a scissors-type handle 270. Squeezing of thescissors-type handle 270 causes each pair of prongs 262A and 262B on theyokes 258 and 260 to move together, thereby compressing their respectiveligation clips about the blood vessel. The scissors-type handle 270includes a latching mechanism 272 which serves to secure the handle 270and thus the ligation clip applicator 252 in a closed or clampedposition. While the ligation clip applicator is held in a clampedposition, the cutting mechanism 254 is actuated, preferably by a plunger274 located at the proximal end of the ligation-cutting tool 250. Theplunger 274 is operably connected to the cutting blade 280, and biasedproximally to urge the blade 280 into its normally retracted position.By moving the plunger 274 distally, the physician causes the cuttingblade 280 to likewise move distally and cut the blood vessel which isretained between the yokes 258 and 260. When the physician releases theplunger 274, the plunger 274 (and thus the cutting blade 280) retractsto its original position. Manipulation of the handle 270 then separatesthe prongs 262A and 262B, leaving the clips in place on the severedportions of the blood vessel, and the ligation cutting tool 250 isremoved.

The shaft 251 of the side biting ligation-cutting tool 250 is a slendermember that is longer than the lumen 38 of the endoscope 30. A housing259 covers those mechanisms on the shaft 251 that transmit themanipulations of the handle 270 and the plunger 274 at the proximal endof the side biting ligation-cutting tool 250 to the clipping and cuttingmotions, respectively, at the distal end of the side bitingligation-cutting tool 250.

The suction-coagulator tool 300 (FIG. 6) is used to remove body fluids(e.g., blood) and reduce bleeding during the vessel harvestingprocedure, and is of the type generally known in the art for thisprocedure. The suction-coagulator tool 300 has an elongated shaft 301and includes a handle 310 attached to the proximal end of shaft 301. Asuction tube 302 is attached to the proximal end of shaft 301 andextends to the distal end of shaft 301. At the distal end of shaft 301the suction tube 302 is open for suctioning body fluids. Also attachedto the proximal end of shaft 301 is a power cable 304 for supplyingpower for tissue coagulation. When button 308 on handle 310 isactivated, the power is supplied to the distal end of shaft 301 tocauterize bleeding tissue, and thus to stop bleeding. Thesuction-coagulator tool 300 controls bleeding in two ways. The suctiontube 302 may be used alone to suction any body fluids from thedissection area, or the coagulator may be used to cauterize the bleedingtissue.

METHOD OF USE

The endoscope 30 and accompanying tools 100, 150, 200, 250 and 300 areused in combination for harvesting a vessel. After proper preparation ofthe incision site, the physician makes a small incision 350 (e.g., 3 cmlong) over the proximal aspect of the blood vessel to be harvested (seeFIGS. 1 and 9). The blood vessel 20 is exposed and dissected for a shortlength under direct vision. As seen in FIG. 9, the blood vessel 20 isthen severed to expose a free end 352 and a free end 353 (which may beclipped as shown in FIG. 9). For example, to remove a saphenous vein,the incision 350 will be made at the groin over the saphenous vein andthe vein will be dissected free from the junction of the common femoralvein. As shown in FIGS. 1 and 9, the gripping forceps 150 is insertedthrough the dissecting ring 110 of the dissecting tool 100, and theassembly of the dissecting tool 100 and the gripping forceps 150 isinserted through the lumen 38 of the endoscope 30 such that the distalends of the dissecting tool 100 and gripping forceps 150 extend beyondthe distal end of the lumen 38. The physician then grasps the free end352 of the blood vessel 20 with the gripping forceps 150 and holds itunder tension. The dissecting tool 100 is then advanced distally(together with the endoscope 30) over the distal end of the grippingforceps 150 and over the blood vessel 20. As the dissecting tool 100 ismanipulated by the physician, the blood vessel 20 is dissected away fromthe surrounding connective tissue.

As illustrated in FIG. 10 (which has a portion of the patient's bodybroken away to show the invention in operation), the dissection processproceeds distally along the blood vessel 20, and the endoscope 30 isadvanced along with the dissecting tool 100 into the incision 350. Untilthis point, the physician has been viewing the procedure under directvision. Now, the physician switches to viewing the dissection process(occurring at the area immediately adjacent the distal end of the lumen38) through the fiber optic viewing device 42 located at the distal endof the scope body 34 of the endoscope 30. The illumination source 40provides adequate lighting for the physician to view the dissection andtool operations occurring within the patient via the monitor. Irrigantis introduced as necessary through the irrigation channel 48 of theendoscope 30 to keep blood or other body tissue from obscuring visionadjacent the distal end of the scope body 34 of the endoscope.

As the dissection tool 100 is advanced along the blood vessel 20, a sidebranch 22 of the blood vessel 20 may be encountered before the desiredlength of blood vessel 20 has been dissected. When the physician reachesa side branch 22 before obtaining the desired length of blood vessel 20,the ligation-cutting tool 200 is employed to sever the side branch 22from the vessel being harvested (blood vessel 20).

When a side branch 22 is reached, the physician stops advancing thedissecting tool 100 and endoscope 30 and, if necessary, withdraws thedissecting tool 100 proximally from the side branch 22 to provide roomfor operation of the ligation-cutting tool 200. The ligation-cuttingtool 200 is inserted into the proximal end of the lumen 38 and advanceddistally through the lumen 38 and into the area distal of the scope body34 of the endoscope 30. Using the illumination source 40 and the viewingdevice 42, the physician positions the ligation-cutting tool 200 overthe side branch 22 such that the side branch 22 is sitting in the yokes208 and 210 (see FIG. 11). The physician then manipulates the handle 220of the ligation-cutting tool 200 to actuate the ligation clip applicator202. As the prongs 212A and 212B on each of the yokes 208 and 210 movetoward each other, the ligation clips 216 are clamped about the sidebranch 22, thereby stopping blood flow through the side branch 22.

While the side branch 22 is held securely between the yokes 208 and 210of the ligation clip applicator 202, the physician pushes the plunger224 to activate the cutting mechanism 204. As shown in FIG. 12, thecutting blade 230 thus moves distally into and through the side branch22, thereby severing the side branch 22 from the blood vessel 20 betweenthe ligation clips 216. When the plunger 224 is released by thephysician, the cutting blade 230 returns to its original retractedposition. The handle 220 is then manipulated to separate the prongs 212Aand 212B, and the ligation-cutting tool 200 is withdrawn proximallythrough the lumen 38 of the endoscope 30. The ligation-cutting tool 200may then be prepared to be used again later in the procedure (i.e.,reloaded with additional clips 216), if required.

After the ligation-cutting tool 200 has been removed from the endoscope,the dissecting tool 100 and endoscope 30 are again advanced distallyalong the blood vessel 20 (as previously described) until another sidebranch is reached. In this regard, the dissecting ring 110 is largeenough to pass over the clipped and severed stumps of any side branches22 which extend from the blood vessel 20. The ligation-cutting tool 200is then used as previously described to sever additional side branchesfrom the blood vessel 20. The procedure is repeated until the desiredlength of blood vessel 20 has been dissected free from the surroundingtissue and side branches. During the dissection procedure, thesuction-coagulator tool 300 is used as required to control bleeding,again under the constant vigilance of the physician through theendoscope 30. During the entire procedure, the blood vessel 20 has beenheld in tension by the physician via the gripping tool 150. In addition,as more and more of the blood vessel 20 becomes dissected, the endoscope30 is advanced distally into the patient's body and the blood vessel 20is moved into the lumen 38 of the scope body 34.

When the desired length of blood vessel 20 has been dissected free fromthe surrounding connective tissue, the dissecting tool 100 is movedproximally away from the distal end of the dissected segment, and theside-biting ligation-cutting tool 250 is inserted into the proximal endof the lumen 38 and advanced distally through the lumen 38 into the areaadjacent the distal end of the scope body 34 and the distal end of thedissected blood vessel 20. The side-biting ligation-cutting tool 250 ispositioned such that the blood vessel 20 is between the first yoke 258and the second yoke 260 of the ligation clip applicator 252. When theblood vessel 20 is properly positioned between yokes 258 and 260, thephysician manipulates the handle 270 to actuate the ligation clipapplicator 252. As the yokes 258 and 260 move toward each other, theyokes 258 and 260 act to pinch the ligation clips 266 over the distalend of the dissected blood vessel 20 (thus stopping blood flow throughthe blood vessel 20). While the blood vessel 20 is held securely by theligation clip applicator 252, the physician pushes the plunger 274 toactivate the cutting mechanism 254. The cutting blade 280 advancesbetween the ligation clips 266 and through the blood vessel 20 to severthe blood vessel 20 into a freed section 360 having free end 352 (FIG.10) and a free end 361 (FIG. 13) and a remaining section 362. When theplunger 274 is released by the physician, the cutting blade 280 returnsto its retracted position. The handle 270 is manipulated to separate theprongs 262A and 262B, and the side-biting ligation-cutting tool 250 iswithdrawn proximally through the lumen 38 of the endoscope 30. The tool250 may apply ligation clips on sections 360 and 362, or just one clipon the remaining section 362 of the blood vessel 20.

The freed section 360 of the blood vessel 20 is now free of allconnections to the patient's body and is substantially within the lumen38 of the endoscope 30. While gripping the now dissected blood vessel 20with the gripping forceps 150, the physician may simultaneously removethe scope body 34 of the endoscope 30 and the enclosed segment of bloodvessel 20 from the body of the patient. After the endoscope 30 and freedsection 360 of blood vessel 20 are removed from the patient, thephysician closes the incision 350 in the patient's body to complete thevessel harvesting procedure. The freed section 360 of the blood vessel20 may then be removed from the lumen 38 of the endoscope 30 andprepared for its intended end use. The vessel harvesting procedure hasbeen accomplished with only a single small incision, yet the physiciancan see the entire working portion of the procedure for manipulation ofthe tools to accomplish dissection, ligation and severing of the freedsection 360 of the blood vessel 20. This results in less trauma to thepatient than was previously attainable, with a much more precise andefficient procedure, both in terms of affecting the tissue surroundingthe dissected vessel, and in terms of the timing and control of theprocedure by the physician.

Occasionally, it is desired to remove a continuous length of a bloodvessel that is longer than the scope body of the inventive endoscope. Inthis instance, the physician is unable to advance the endoscope and itsrelated tools far enough from the original small incision into thepatient to harvest a segment of the desired length. If no endoscopescope body is long enough to harvest a blood vessel segment of thedesired length, the physician may make a second incision in the patientadjacent that point on the blood vessel where the dissection has reachedvia the use of the endoscope and related tools through the firstincision. This is illustrated in FIG. 14.

FIG. 14 illustrates a portion of a patient's leg. A first incision 350has been made in the patient and the blood vessel 20 severed to createfree ends 353 and 352. A portion of the desired segment of the bloodvessel (to the left of the incision 350 in FIG. 14) has been dissected,ligated and clipped from the surrounding tissue and side branches 22,using the inventive endoscope and tools in a manner as discussed above.The desired segment of the blood vessel (designated as segment 400 inFIG. 14) is not severed using the side-biting ligation-cutting tool 250through the scope body 34 of the endoscope 30. Instead, a secondincision 450 is made in the patient adjacent that point where thedissection of the blood vessel 20 has reached. This second incision thusexposes that portion of the blood vessel 20 which has been dissectedfrom the surrounding connective tissue of the patient's body (segment400). The physician releases the free end 352 of the blood vessel 20(which has been continually held by the gripping forceps 150) andproximally withdraws the endoscope 30 and all of its associated toolswhich are still in the patient's body. Working through the secondincision 450, the physician then grips the exposed portion of the bloodvessel 20 and pulls the dissected segment 400 of the blood vessel 20through the second incision, in direction of arrow 455 as illustrated inFIG. 14.

Once the entire dissected segment 400 has been pulled out of the patientthrough the second incision 450, further dissection of the remainingportion of the blood vessel 20 within the patient can continue using theinventive tools and method. As previously described, the grippingforceps 150 is inserted through the dissecting ring 110 of thedissecting tool 100 and the assembly of the dissecting tool 100 and thegripping forceps 150 is inserted into the proximal end of the lumen 38and advanced distally through the lumen 38. The gripping forceps 150 isagain used to hold the free end 352 of the segment 400 of the bloodvessel 20 during the continued procedure. The endoscope 30 anddissecting tool 100 are distally advanced over the blood vessel 20 andinto the patient's body through the second incision 450. The physicianthen continues to dissect the blood vessel 20 away from the surroundingconnective tissue with the dissecting tool 100, ligating and severingside branches 22 as they are encountered using the ligation-cutting tool150. The suction-coagulator tool 300 is also used as necessary duringcontinued dissection and side branch severing. This process may berepeated until the desired length of blood vessel 20 has been harvested.At this point, the side-biting ligation-cutting tool 250 is employedthrough the second incision 450 and endoscope 30 to sever the bloodvessel 20 from the patient in the desired length. The severed bloodvessel is then withdrawn, along with the endoscope 30 and any relatedtools remaining within the patient, from the patient through the secondincision 450. The severed blood vessel is removed from the endoscope andthen treated as necessary for further use. The incisions 350 and 450 arethen closed up, with minimal trauma to the patient. For instance, atwo-step vessel harvesting procedure such as illustrated in FIG. 14 mayresult in the harvesting of a vessel as long as twelve to fifteeninches, with only two separate 3 cm long incisions made in the patient'sskin. The entire procedure, as conducted using the inventive endoscopeand its related tools, has been conducted under direct vision orendoscopic vision by the physician and is thus much more effective,efficient and elegant than prior vessel harvesting techniques.

CONCLUSION

The present invention permits a discrete segment of a blood vessel to beharvested with only a small incision in the body of a patient (or morethan one small incision if a very long segment is desired). Theinventive endoscope and its unique tools eliminate the need for a fulllength incision along the length of the blood vessel in order to harvesta segment of the blood vessel. Use of the inventive endoscope and toolseliminates the need for a second incision at the distal end of thedesired segment of the blood vessel in order to sever the desiredsegment from the patient's body, and also allows vessel harvesting witha relatively small incision. Proximal incisions heal easier and morereadily than distal incisions in most patients, and particularly forthose with poor circulation in their extremities. The illuminationsource and the viewing device of the inventive endoscope allow thephysician to directly view the dissection in process, which results in avery precise and controlled dissection of the blood vessel. At the sametime, the use of the ligation-cutting tool and the side-bitingligation-cutting tool allows the physician to control bleeding bycutting and sealing off side branches to the blood vessel and the vesselitself in a secure and permanent manner. Nothing is inserted within theblood vessel being harvested during the procedure, so vessel integrityis maintained. Accordingly, undesired trauma to the vessel beingharvested and to its surrounding connective tissue is minimized.

Although the present invention has been described with reference topreferred embodiments, workers skilled in the art will recognize thatchanges may be made in form and detail without departing from the spiritand scope of the invention.

What is claimed:
 1. A method of harvesting a section of a vessel from apatient's body as living tissue for use in a different environment ofthe patient's body comprising:providing an endoscope of the type havinga scope body with a lumen extending longitudinally therethrough, withthe lumen having a proximal end and a distal end, and means for viewingan area adjacent the distal end of the lumen, the lumen having a lateraldimension of size sufficient to accommodate the vessel and a tool foruse in harvesting the vessel; exposing a first end of the vessel sectionto be harvested through an incision in the patient's body; gripping thefirst end with a gripping tool that has been inserted through the lumenof the endoscope; and dissecting the vessel away from surroundingconnective tissue of the patient's body with a dissecting tool insertedthrough the lumen of the endoscope, using the viewing means to view thedissection in process.Iadd.; cutting the vessel at proximal and distalends of the vessel section; and removing the vessel section from thepatient's body, the steps of exposing, gripping, dissecting, cutting andremoving being performed in a manner that minimizes damage to theendothelium of the vessel.Iaddend..
 2. The method of harvesting a vesselaccording to claim 1, including:advancing the endoscope and thedissecting tool along the vessel until a side branch of the vessel isencountered.
 3. The method of harvesting a vessel according to claim 2,including:applying a ligation member to the branch and cutting thebranch between the vessel and the ligation member with aligating-cutting tool inserted through the lumen.
 4. The method ofharvesting a vessel according to claim 3, including:repeating theadvancing and applying steps until the endoscope is fully inserted or adesired length of the vessel is reached.
 5. The method of harvesting avessel according to claim 1, including:controlling bleeding as necessarywith a bleeding control tool inserted through the lumen.
 6. The methodof harvesting a vessel according to claim 1, including:ligating andcutting the distal end of the vessel with a transecting tool insertedthrough the lumen, allowing a segment of the vessel to be removedwithout making a second incision in the patient's body.
 7. The method ofharvesting a vessel according to claim 1, including:making a secondincision in the patient's body spaced from the first incision; exposingthat portion of the vessel which has been dissected from surroundingtissue of the patient's body through the second incision in thepatient's body; gripping the exposed portion of the vessel which hasbeen dissected and that has been inserted through the lumen of theendoscope; advancing the endoscope over the vessel and into thepatient's body through the second incision; and continuing to dissectthe vessel away from surrounding connective tissue of the patient's bodywith a dissecting tool inserted through the lumen of the endoscope,using the viewing means to view the continued dissection in process. 8.A method of removing a section of a vessel from a patient's body for usein a different environment comprising:providing an endoscope of the typehaving a scope body with a lumen extending longitudinally therethrough,with the lumen having a proximal end and a distal end, and means forviewing an area adjacent to the distal end of the lumen, the lumenhaving a lateral dimension of size sufficient to accommodate thatsection of the vessel which is being removed and a tool for use inremoving the section of the vessel; exposing a portion of the section ofthe vessel to be removed through an incision in the patient's body;gripping the exposed portion with a gripping tool that has been insertedthrough the lumen of the endoscope; and dissecting the section of thevessel which is being removed from the patient's body with a dissectingtool also inserted through the lumen of the endoscope, using the viewingmeans to view the dissection process.Iadd.; cutting the vessel atproximal and distal ends of the vessel section; and removing the vesselsection from the patient's body, the steps of exposing, gripping,dissecting, cutting and removing being performed in a manner thatminimizes damage to the endothelium of the vessel.Iaddend..
 9. Themethod of removing a section of a vessel according to claim 8, andfurther including:removing the section of the vessel through the lumenof the endoscope.
 10. The method of removing a section of a vesselaccording to claim 8, and further including:advancing the endoscope andthe dissecting tool along the vessel until a branch of the vessel isencountered.
 11. The method of removing a section of a vessel accordingto claim 10, and further including:applying a ligation member to thevessel branch and cutting the branch with a ligating-cutting toolinserted through the lumen.
 12. The method of removing a section of avessel according to claim 11, and further including:repeating theadvancing and applying steps until the endoscope is fully inserted orthe desired amount of the vessel is dissected.
 13. The method ofremoving a section of a vessel according to claim 8, and furtherincluding:controlling bleeding as necessary with a bleeding control toolinserted through the lumen. .Iadd.
 14. The method of claim 1 furthercomprising re-using the vessel section as a fluid conduit in anotherpart of the patient's body. .Iaddend..Iadd.15. The method of claim 8further comprising re-using the vessel section as a fluid conduit in ahuman body. .Iaddend..Iadd.16. A method of harvesting a section of avessel from a patient's body for use in a different environmentcomprising:making an incision over a first end of the vessel section tobe harvested, the length of the incision being sufficient to accommodateat least one tool used in harvesting the vessel section but beingsubstantially smaller than the length of the vessel section; exposingthe first end of the vessel section through the incision; dissecting thevessel away from surrounding tissue of the patient's body until adesired length of vessel which exceeds the length of the incision hasbeen dissected free from surrounding tissue; severing the vessel atproximal and distal ends of the vessel section with at least one toolinserted through the incision; and removing the vessel section throughthe incision, the steps of making an incision, exposing, dissecting,severing, and removing being performed in a manner that minimizes damageto the endothelium of the vessel. .Iaddend..Iadd.17. The method ofharvesting a vessel according to claim 16, including: applying aligation member to the vessel in a position distal to the distal end ofthe vessel section. .Iaddend..Iadd.18. The method of harvesting a vesselaccording to claim 16, including; controlling bleeding as necessary..Iaddend..Iadd.19. The method of harvesting a vessel according to claim16, including: applying a ligation member to a side branch of thevessel; and severing the side branch of the vessel between the ligationmember and the vessel. .Iaddend..Iadd.20. The method of claim 16 furthercomprising re-using the vessel section as a fluid conduit in a humanbody. .Iaddend..Iadd.21. The method of claim 16 further comprisingre-using the vessel section as a fluid conduit in another part of thepatient's body. .Iaddend..Iadd.22. A method of harvesting a section of avessel from a patient's body for use in a different environmentcomprising:making an incision in the patient's body over a first end ofthe vessel section to be harvested, the length of the incision beingsufficient to accommodate at least one tool used in harvesting thevessel section but being substantially smaller than the length of thevessel section; exposing the first end of the vessel section to beharvested through the incision in the patient's body; dissecting thevessel away from surrounding tissue of the patient's body; and viewingthe dissection of the vessel with a viewing device inserted through theincision; severing the vessel at proximal and distal ends of the vesselsection; and removing the vessel section from the patient's body, thesteps of making an incision, exposing, dissecting, viewing, severing andremoving being performed in a manner that minimizes damage to theendothelium of the vessel. .Iaddend..Iadd.23. The method of harvesting avessel according to claim 22, including: applying a ligation member to aside branch of the vessel; and severing the side branch between thevessel and the ligation member. .Iaddend..Iadd.24. The method ofharvesting a vessel according to claim 23, including; repeating thedissecting step until a desired length of the vessel section has beendissected. .Iaddend..Iadd.25. The method of harvesting a vesselaccording to claim 24, including: severing the distal end of the vesselsection; and removing the vessel section through the incision..Iaddend..Iadd.26. The method of harvesting a vessel according to claim22, including; repeating the dissecting step until a desired length ofthe vessel section has been dissected. .Iaddend..Iadd.27. The method ofharvesting a vessel according to claim 26, including:severing the distalend of the vessel section; and removing the vessel section through theincision. .Iaddend..Iadd.28. The method of harvesting a vessel accordingto claim 22, including: controlling bleeding as necessary..Iaddend..Iadd.29. The method of claim 20 further comprising re-usingthe vessel section as a fluid conduit in a human body..Iaddend..Iadd.30. The method of claim 22 further comprising re-usingthe vessel section as a fluid conduit in another part of the patient'sbody. .Iaddend..Iadd.31. A method of harvesting a section of a vesselfrom a patient's body for use in a different environment comprising:providing a device having an elongated body, the body having a lumenextending longitudinally therethrough, the lumen having a proximal endand a distal end and having a lateral dimension of size sufficient toaccommodate the vessel and a tool for use in harvesting the vessel;exposing a first end of the vessel section to be harvested through anincision in the patient's body; gripping the first end with a grippingtool that has been inserted through the lumen of the elongated body;dissecting the vessel away from surrounding tissue of the patient's bodywith a dissecting tool inserted through the incision; and viewing thedissection of the vessel from an area adjacent the distal end of thelumen of the elongated body; severing the vessel at proximal and distalends of the vessel section; and removing the vessel section from thepatient's body, the steps of exposing, gripping, dissecting, viewing,severing and removing being performed in a manner that minimizes damageto the endothelium of the vessel. .Iaddend..Iadd.32. The method ofharvesting a vessel according to claim 31, including: advancing theelongated body and the dissecting tool along the vessel until a sidebranch of the vessel is encountered. .Iaddend..Iadd.33. The method ofharvesting a vessel according to claim 32, including:applying a ligationmember to the branch and cutting the branch between the vessel and theligation member with a ligating-cutting tool inserted through the lumen..Iaddend..Iadd.34. The method of harvesting a vessel according to claim33, including: repeating the advancing and applying steps until theelongated body is fully inserted or a desired length of the vessel isreached. .Iaddend..Iadd.35. The method of harvesting a vessel accordingto claim 31, including: controlling bleeding as necessary with ableeding control tube inserted through the lumen. .Iaddend..Iadd.36. Themethod of harvesting a vessel according to claim 31, including: ligatingand cutting the distal end of the vessel with a transecting toolinserted through the lumen, allowing the vessel section to be removedwithout making a second incision in the patient's body..Iaddend..Iadd.37. The method of harvesting a vessel according to claim31, including: making a second incision in the patient's body spacedfrom the first incision; exposing that portion of the vessel which hasbeen dissected from surrounding tissue of the patient's body through thesecond incision in the patient's body; gripping the exposed portion ofthe vessel which has been dissected with a gripping tool that has beeninserted through the lumen of the elongated body; advancing theelongated body over the vessel and into the patient's body through thesecond incision; and continuing to dissect the vessel away fromsurrounding tissue of the patient's body with a dissecting tool insertedthrough the second incision. .Iaddend..Iadd.38. The method of claim 31further comprising re-using the vessel section as a fluid conduit in ahuman body. .Iaddend..Iadd.39. The method of claim 3 further comprisingre-using the vessel section as a fluid conduit in another part of thepatient's body. .Iaddend..Iadd.40. A method of harvesting a section of avessel from a patient's body for use in a different environmentcomprising:making an incision over a first end of the vessel section tobe harvested, the length of the incision being sufficient to accommodateat least one tool used in harvesting the vessel section but beingsubstantially smaller than the length of the vessel section; exposingthe first end of the vessel section through the incision; dissecting thevessel away from surrounding tissue of the patient's body with adissecting tool inserted through the incision until a desired length ofvessel which exceeds the length of the incision has been dissected freefrom surrounding tissue; viewing the dissection of the vessel with aviewing device inserted through the incision; severing the vessel atproximal and distal ends of the vessel; and removing the vessel sectionfrom the patient's body, the steps of making an incision, exposing,dissecting, viewing, severing, and removing being performed in a mannerthat minimizes damage to the endothelium of the vessel..Iaddend..Iadd.41. The method of claim 40 further comprising re-usingthe vessel section as a fluid conduit in a human body..Iaddend..Iadd.42. The method of claim 40 further comprising re-usingthe vessel section as a fluid conduit in another part of the patient'sbody. .Iaddend..Iadd.43. The method of harvesting a vessel according toclaim 40, including: applying a ligation member to the vessel in aposition distal to the distal end of the vessel section..Iaddend..Iadd.44. The method of harvesting a vessel according to claim40, including; controlling bleeding as necessary. .Iaddend..Iadd.45. Themethod of harvesting a vessel according to claim 40, including:litigating a branch of the vessel; and severing the branch of the vesselbetween the ligation and the vessel. .Iaddend..Iadd.46. The method ofharvesting a vessel according to claim 40 including maintaining thelumen of the vessel clear of any tools and other objects used in theharvesting procedure. .Iaddend..Iadd.47. The method of harvesting avessel according to claim 40 including making a second incision in thepatient's body spaced from the first incision, the second incision beingsubstantially smaller than the length of the vessel section, and whereinthe vessel section is removed through the second incision..Iaddend..Iadd.48. A method of harvesting a section of a vessel from apatient's body for use in a different environment comprising:making anincision over a first end of the vessel section to be harvested, thelength of the incision being sufficient to accommodate at least one toolused in harvesting the vessel section but being substantially smallerthan the length of the vessel section; exposing the first end of thevessel section through the incision; dissecting the vessel away fromsurrounding tissue of the patient's body until a desired length ofvessel which exceeds the length of the incision has been dissected freefrom surrounding tissue; severing the vessel at proximal and distal endsof the vessel section with at least one tool inserted through theincision; removing the vessel section through the incision; and re-usingthe vessel section as a fluid conduit in a human body..Iaddend..Iadd.49. A method of harvesting a section of a vessel from apatient's body for use in a different environment comprising:making anincision in the patient's body over a first end of the vessel section tobe harvested, the length of the incision being sufficient to accommodateat least one tool used in harvesting the vessel section but beingsubstantially smaller than the length of the vessel section; exposingthe first end of the vessel section to be harvested through the incisionin the patient's body; dissecting the vessel away from surroundingtissue of the patient's body; and viewing the dissection of the vesselwith a viewing device inserted through the incision; severing the vesselat proximal and distal ends of the vessel section; removing the vesselsection from the patient's body; and re-using the vessel section as afluid conduit in a human body. .Iaddend..Iadd.50. A method of harvestinga section of a vessel from a patient's body for use in a differentenvironment comprising: providing a device having an elongated body, thebody having a lumen extending longitudinally therethrough, the lumenhaving a proximal end and a distal end and having a lateral dimension ofsize sufficient to accommodate the vessel and a tool for use inharvesting the vessel; exposing a first end of the vessel section to beharvested through an incision in the patient's body; gripping the firstend with a gripping tool that has been inserted through the lumen of theelongated body; dissecting the vessel away from surrounding tissue ofthe patient's body with a dissecting tool inserted through the incision;and viewing the dissection of the vessel from an area adjacent thedistal end of the lumen of the elongated body; severing the vessel atproximal and distal ends of the vessel section; removing the vesselsection from the patient's body; and re-using the vessel section as afluid conduit in a human body. .Iaddend..Iadd.51. A method of harvestinga section of a vessel from a patient's body for use in a differentenvironment comprising:making an incision over a first end of the vesselsection to be harvested, the length of the incision being sufficient toaccommodate at least one tool used in harvesting the vessel section butbeing substantially smaller than the length of the vessel section;exposing the first end of the vessel section through the incision;dissecting the vessel away from surrounding tissue of the patient's bodywith a dissecting tool inserted through the incision until a desiredlength of vessel which exceeds the length of the incision has beendissected free from surrounding tissue; viewing the dissection of thevessel with a viewing device inserted through the incision; severing thevessel at proximal and distal ends of the vessel; removing the vesselsection from the patient's body; and re-using the vessel section as afluid conduit in a human body. .Iaddend..Iadd.52. A method of re-using asection of a vessel from a patient's body in the patient's bodycomprising:making an incision over a first end of the vessel section,the length of the incision being sufficient to accommodate at least onetool used in the method but being substantially smaller than the lengthof the vessel section; exposing the first end of the vessel sectionthrough the incision; dissecting the vessel away from surrounding tissueof the patient's body with a tool inserted through the incision until adesired length of vessel which exceeds the length of the incision hasbeen dissected free from surrounding tissue; severing the first end ofthe vessel section with a tool inserted through the incision; andre-using the vessel section as a fluid conduit in the patient's body..Iaddend.